It looks like loadpano won't ever call your <krpano onstart="" code...
Seems like there should be a parameter for loading a new xml clean.
also loadpano can not remove any plugins that were added with addplugin.
I tried ignorekeep, null etc,, and all my xml thumbnails were still there from the last xml.
For now it looks like the best way is openurl instead.

The thumbs are tour/XML specific. Basically I was try to load a completely new tour without a page refresh. It looks like loadpano can't remove dynamically added plugins. For onstart I guess I can program around it. I don't know why load Pano can't run the new onstart but oh well.

I think the main problem is that for professional plugins, they set variables. Number of items, whether it's been completed etc.
So upon loading a new XML, all these custom variables are STILL set, so previous plugins, might be RECREATED, based on settings from a previous XML.
Is there a way to CLEAR out all previously set variables?

Also, the below first example does NOT work per documentation. There are no additional commands after loadpano. No worries, I worked around it with a delayed call. So the only issue now, is how to remove, reset krpano to "factory defaults"...
without going through a series troubleshooting session, to see which variables need to be RESET to null.

<hotspot name="arrow1124c" ... ondown="fade_hotspots(get(name),0,1,default,WAIT);looktohotspot(get(name),42);loadpano(204,null,IGNOREKEEP,ZOOMBLEND(1,10));" ... />

<hotspot name="arrow1124d" ... ondown="fade_hotspots(get(name),0,1,default,WAIT);looktohotspot(get(name),42);delayedcall(0.1,loadpano(204,null,IGNOREKEEP,ZOOMBLEND(1,10)));" ... />

For example,

<thumbnails name="thumbs1" width="750" edge="leftbottom" align="leftbottom" x="35" y="-6" thumb_width="135" thumb_height="60" thumb_margin="12" frame_width="151" frame_height="72" folow_mouse="false" skin_url="%SWFPATH%/skin/" thumb_url="http://www.seeit360.com/files2/imagecache/krpanothumb" scroll_speed="2" visited_auto="false" >
<thumb name="tn1" url="/volcanbaru360_001.jpg" onclick="loadscene(get(scene[0].name),null,MERGE,BLEND(1));" onhover="showtext('Volcan Baru - Expedition sart from Cerro Punta', buttonstyle);" />
<thumb name="tn2" url="/volcanbaru360_003.jpg" onclick="loadscene(get(scene[1].name),null,MERGE,BLEND(1));" onhover="showtext('Volcan Baru - First Overlook', buttonstyle);" />
<thumb name="tn3" url="/volcanbaru360_002.jpg" onclick="loadscene(get(scene[2].name),null,MERGE,BLEND(1));" onhover="showtext('Volcan Baru - Halfway Point ', buttonstyle);" />
<thumb name="tn4" url="/vp11.jpg" onclick="loadscene(get(scene[3].name),null,MERGE,BLEND(1));" onhover="showtext('Volcan Baru Summit', buttonstyle);" />
<thumb name="tn5" url="/volcanbaru360_005.jpg" onclick="loadscene(get(scene[4].name),null,MERGE,BLEND(1));" onhover="showtext('Volcan Baru - Summit After Sunrise', buttonstyle);" />
</thumbnails>

would supposed to be overwritten by a new one but instead, they only replace the first two in the array, I'm assuming..
I don't think there is a solution here except for using unique names for every single xml.

<thumbnails name="thumbs1" width="750" edge="leftbottom" align="leftbottom" x="35" y="-6" thumb_width="135" thumb_height="60" thumb_margin="12" frame_width="151" frame_height="72" folow_mouse="false" skin_url="%SWFPATH%/skin/" thumb_url="http://www.seeit360.com/files2/imagecache/krpanothumb" scroll_speed="2" visited_auto="false" >
<thumb name="tn1" url="/cerro_brujo.jpg" onclick="loadscene(get(scene[0].name),null,MERGE,BLEND(1));" onhover="showtext('Cerro Brujo Gourmet', buttonstyle);" />
<thumb name="tn2" url="/cerro_brujo2.jpg" onclick="loadscene(get(scene[1].name),null,MERGE,BLEND(1));" onhover="showtext('Cerro Brujo Gourmet: Exterior', buttonstyle);" />
</thumbnails>

I also just tried nesting these INSIDE the SCENE. But it still did not prevent the data from existing beyond its scope.

Thank, I have most everything working now, except for the thumbs that recreate themselves. Is there anyway you see to just reset that object?
I'm not sure that makes any sense. Unless I could reset it just before the XML change.

I didn't realize I could use that in a normal <action as it's not listed in http://krpano.com/docu/actions/
But I'll give it a whirl! Thanks!