Hi,
yes that is possible. There are different ways.
I have this 'moving hotspots pack'.
With this you create timelines and you can control things at a certain time.
That can be any krpano action sort of.
So you can control the distortion/position/rotation/scale/alpha etc etc of a hotspots during playing, but also force lookto at certain times or trigger any action you like at a pre-defined moment.
plugin[vidoe].time could be your friend.
Tuur