Yes, the two (or several) instances would open a websocket connection to the server application, which only acts as a
transfer node between the instances. If all of them are krpano instances, I guess it would be wiser if one is the
master and the other
slaves - at least if you want to coordinate pano movement.
And you would probably prefer to have an Apache module in your webserver to get quick response, but my own homepage is in a web-hotel, so I don't have that possibility. On the other hand, I run an Apache server in my home PC, but I have forgotten how to write an Apache module.
In the meantime, I made another test page, where you can see that it's possible to control
two separate panos with the same remote control:
http://wirestam.com/panos/test/seasons/